September 22, 2014

turkeyinacan:

shoutout to people working weekends and overnights and overtime, people working in hospitality and retail and food service, who are sacrificing time with their loved ones, so fuckers with weekday desk jobs get to live comfortably with the amenities we provide while simultaneously shitting all over us for not getting “real jobs”

(via hermione-ganja)

September 21, 2014
September 20, 2014

neuromorphogenesis:

Hacking The Brain

Abuse of these mind hacking drugs is one of the fastest growing problems of our generation. As long as doctors keep prescribing these harmful drugs to too many youngsters the problem will continue to grow. Although some children really do need these drugs to function regularly, my personal opinion is that the requirements and potency of these drugs should wait until the patient is of age – the same as tobacco or alcohol. The availability of these drugs to young Americans needs to diminish if the trend of usage wants to decrease.

- By AllTreatment

(via neuromorphogenesis)

neuromorphogenesis:

No sedative necessary: Scientists discover new “sleep node” in the brain

A sleep-promoting circuit located deep in the primitive brainstem has revealed how we fall into deep sleep. Discovered by researchers at Harvard School of Medicine and the University at Buffalo School of Medicine and Biomedical Sciences, this is only the second “sleep node” identified in the mammalian brain whose activity appears to be both necessary and sufficient to produce deep sleep.

Published online in Nature Neuroscience, the study demonstrates that fully half of all of the brain’s sleep-promoting activity originates from the parafacial zone (PZ) in the brainstem. The brainstem is a primordial part of the brain that regulates basic functions necessary for survival, such as breathing, blood pressure, heart rate and body temperature.

“The close association of a sleep center with other regions that are critical for life highlights the evolutionary importance of sleep in the brain,” says Caroline E. Bass, assistant professor of Pharmacology and Toxicology in the UB School of Medicine and Biomedical Sciences and a co-author on the paper.

The researchers found that a specific type of neuron in the PZ that makes the neurotransmitter gamma-aminobutyric acid (GABA) is responsible for deep sleep. They used a set of innovative tools to precisely control these neurons remotely, in essence giving them the ability to turn the neurons on and off at will.

 “These new molecular approaches allow unprecedented control over brain function at the cellular level,” says Christelle Ancelet, postdoctoral fellow at Harvard School of Medicine. “Before these tools were developed, we often used ‘electrical stimulation’ to activate a region, but the problem is that doing so stimulates everything the electrode touches and even surrounding areas it didn’t. It was a sledgehammer approach, when what we needed was a scalpel.”

“To get the precision required for these experiments, we introduced a virus into the PZ that expressed a ‘designer’ receptor on GABA neurons only but didn’t otherwise alter brain function,” explains Patrick Fuller, assistant professor at Harvard and senior author on the paper. “When we turned on the GABA neurons in the PZ, the animals quickly fell into a deep sleep without the use of sedatives or sleep aids.”

How these neurons interact in the brain with other sleep and wake-promoting brain regions still need to be studied, the researchers say, but eventually these findings may translate into new medications for treating sleep disorders, including insomnia, and the development of better and safer anesthetics.

“We are at a truly transformative point in neuroscience,” says Bass, “where the use of designer genes gives us unprecedented ability to control the brain. We can now answer fundamental questions of brain function, which have traditionally been beyond our reach, including the ‘why’ of sleep, one of the more enduring mysteries in the neurosciences.”

September 17, 2014
5th-avenue-nyc:

hadeiadel:

First day at school, Gaza, Palestine.

I can’t stand what these children have to go through it’s so heart breaking

5th-avenue-nyc:

hadeiadel:

First day at school, Gaza, Palestine.

I can’t stand what these children have to go through it’s so heart breaking

(via palmares-politics)

September 16, 2014
September 13, 2014
September 10, 2014

icarusbarnes:

spacehamsters:

chapter29-thelostdiadem:

johnrom:

If the dinosaurs from Jurassic Park said “Hey!” instead of roaring. 

(via leviathanbones)